Best Hotels Near I-75 in Lexington, Kentucky

We checked thousands of reviews on and to find the best hotels for your stay
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Adham Koenderink

Updated: 29 January 2024 · 3 min

Nestled in the center of the Bluegrass Region, Lexington is a vibrant city known for its rich history, horse farms, and bourbons. For travelers looking to explore the area's charm, finding the right accommodation is key. Strategically located hotels near Interstate 75 offer not only convenience to those passing through but also easy access to Lexington's array of attractions.

Choosing to stay at a hotel near I-75 in Lexington means you’re never too far from the action. Whether it's visiting the Kentucky Horse Park, exploring the historic district, or enjoying a distillery tour, you're just a short drive away. Such locations prove ideal for those seeking a mix of leisure activities, business, and scenic drives through the picturesque landscapes of Kentucky.

Moreover, hotels in this corridor are diverse, catering to a range of preferences and budgets. From luxurious accommodations boasting top-notch amenities to cozy, budget-friendly rooms perfect for the frugal traveler, there’s something for everyone. As you plan your Lexington visit, consider these conveniently situated hotels as your base to experience the best of Kentucky charm and hospitality.
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Our Top 6

(Sorted by rating & number of reviews)

1. Comfort Inn & Suites
2. Red Roof Inn Lexington, Nc
3. Holiday Inn Express & Suites Lexington North West-The Vineyard, An Ihg Hotel
4. Quality Inn & Suites
5. Days Inn By Wyndham Lexington
6. Hampton Inn Lexington

Lexington KY Hotels Near I-75 for Family Vacations

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Lexington
Dec 07, 2025 - Dec 08, 2025

Comfort Inn & Suites

7.9

Good

(147 Reviews)

+ 34 photos
Comfort Inn & Suites stands as a beacon of warmth and hospitality for families traveling through Lexington. This hotel, a stone's throw away from I-75, guarantees not just comfort by name but through its actions and offerings. Each room is designed with families in mind, offering ample space and the convenience of in-room microwaves and refrigerators. The hotel boasts an indoor pool, perfect for letting kids splash around after a day of adventure. The complimentary breakfast with waffles will be a hit among the little ones, ensuring they have the energy for a day of exploration. Its strategic location near I-75 allows for quick access to downtown Lexington and its plethora of family-oriented activities.
Address: 1525 Cotton Grove Road
Rating: Good 7.9 (147 Reviews)
Rooms: 30
Price: From 70$

Red Roof Inn Lexington, Nc

5.3

Good

(13 Reviews)

+ 23 photos
While not in Lexington but rather in Lexington and assuming readers might be interested in options along the broader I-75 corridor that extends beyond Kentucky, it's important to mention the Red Roof Inn Lexington offers basic, yet reliable accommodations tailored for guests traveling on business. With free Wi-Fi, a pet-friendly policy, and a focus on comfort and simplicity, it provides a straightforward stay. Its proximity to interstate highways makes zipping in and out of town easy, catering to the no-frills business traveler looking for efficiency and affordability.
Address: 1631 Cotton Grove Rd
Rating: Good 5.3 (13 Reviews)
Rooms: 45
Price: From 90$

Lexington KY Hotels Near I-75 for Business Travelers

For the business traveler, Lexington offers a variety of hotels near I-75 that combine convenience with functionality. These establishments understand the needs of those on the go, offering amenities like high-speed internet, business centers, and meeting spaces. Proximity to I-75 allows for easy transit to Lexington’s downtown business district, the Kentucky Horse Park, and nearby airports, making them ideal for travelers looking to balance work and a bit of leisure. In this section, explore three hotels that stand out for their commitment to serving the business community, ensuring a productive and hassle-free stay.

Holiday Inn Express & Suites Lexington North West-The Vineyard, An Ihg Hotel

8.1

Good

(125 Reviews)

+ 135 photos
Immerse your family in the center of Bluegrass Country by staying at the Holiday Inn Express & Suites Lexington North West-The Vineyard. Perfectly positioned near I-75, this hotel is an ideal choice for families seeking convenience and quality. Guests can expect spacious suites that provide comfort for the whole family, complete with cozy bedding and a choice of pillows for a restful night's sleep. The indoor pool is a hit among kids, while parents will appreciate the fitness center and the complimentary Express Start Breakfast Bar, featuring a range of healthy and indulgent options. The hotel's close proximity to family-friendly attractions, combined with its modern facilities, make it an unbeatable choice for those traveling with children.
Address: 351 Vineyards Crossing
Rating: Good 8.1 (125 Reviews)
Rooms: 88
Price: From 109$

Quality Inn & Suites

8.0

Good

(402 Reviews)

+ 170 photos
Quality Inn & Suites stands as a testament to comfortable stays that don’t compromise on value for the traveling professional. Situated conveniently near I-75, this hotel offers ease of access to Lexington’s corporate and entertainment districts. Guests can take advantage of the in-room desks, free Wi-Fi for staying connected, and fitness center for a quick workout before the day begins. The complimentary hot breakfast is a boon for busy mornings, and the friendly staff are always ready to assist with business needs, including fax and copy services. Its strategic location and thoughtful amenities make it a popular choice among business travelers.
Address: 101 Plaza Parkway
Rating: Good 8.0 (402 Reviews)
Rooms: 61
Price: From 120$

Days Inn By Wyndham Lexington

7.5

Good

(856 Reviews)

+ 52 photos
Days Inn by Wyndham Lexington provides the quintessential home base for business travelers seeking comfort and convenience near I-75. Recognized for its value and service, this hotel offers guests free high-speed internet and a business center designed to meet the needs of those on the road for work. The rooms are equipped with workspaces, and the complimentary breakfast ensures a good start to a bustling day. Its location not only provides quick access to I-75 but also places guests within a comfortable distance of Lexington’s business venues and dining options, making it an efficient choice for those with a packed schedule.
Address: 1620 Cotton Grove Road
Rating: Good 7.5 (856 Reviews)
Rooms: 120
Price: From 73$

Hampton Inn Lexington

8.8

Good

(212 Reviews)

+ 90 photos
The Hampton Inn Lexington encompasses everything a family could need for a comfortable and enjoyable stay. Located conveniently near I-75, this hotel offers easy access to the heart of horse country, while also providing a peaceful retreat at the end of a busy day exploring. Families can enjoy spacious rooms equipped with modern amenities, a complimentary hot breakfast to start the day right, and an indoor pool that promises fun regardless of the weather. The attentive staff are always on hand to ensure your stay is seamless, recommending family-friendly dining and activities nearby. Plus, with its proximity to major attractions, it’s the perfect pitstop for families looking to immerse in Lexington’s charm without the fuss of long travel times.
Address: 1245 Fairview Drive
Rating: Good 8.8 (212 Reviews)
Rooms: 82
Price: From 110$